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Showing posts with the label aldosterone antagonist

Eplerenone, Structure, Mechanism of Action, Drug Interactions, Therapeutic Uses, Adverse effects

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Eplerenone Eplerenone, sold under the brand name Inspra, is an aldosterone antagonist type of potassium-sparing diuretic that is used to treat chronic heart failure and high blood pressure, particularly for patients with resistant hypertension due to elevated aldosterone. Some of the commonbrand names under which eplerenone is marketed include: Inspra Eplenerone Cardiostat Apo-Eplerenone (in some countries) Selara (in some countries) Please note that brand names may vary depending on the country and manufacturer. It is always best to consult with a healthcare professional or pharmacist for accurate and up-to-date information about brand names in your specific region. Mechanism Of Action Eplerenone is a medication classified as a mineralocorticoid receptor antagonist. Its mechanism of action involves selectively blocking the binding of aldosterone, a hormone involved in regulating salt and water balance in the body, to its mineralocorticoid receptors. By blocking the mineralocorticoid r...