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Showing posts with the label Sodium channel blockers

Quinidine, Structure, Mechanism of action, Drug Interactions, Therapeutic Uses, Adverse effects and Contraindications

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  Quinidine Quinidine is an antiarrhythmic drug classified as a Class Ia sodium channel blocker. It is used to treat various types of arrhythmias, particularly supraventricular and ventricular arrhythmias. Quinidine works by blocking sodium channels in the heart muscle, which slows down the conduction of electrical impulses and helps restore a more regular heart rhythm. Quinidine is available under various brand names, depending on the country and manufacturer. Some common brand names for quinidine include: Quinaglute Quinidex Cardioquin Duraquin Quinora Quinalan Quiniduran Quin-Release Quinoric Quinamm It's important to note that the availability of specific brand names may vary by region, and there might be other brand names not listed here. Mechanism Of Action The MOA (Mechanism of Action) of quinidine is related to its classification as a Class Ia antiarrhythmic drug. Quinidine works primarily by blocking sodium channels in cardiac cells during the action potential, affecting t...

Procainamide, Structure, Mechanism of action, Drug Interactions, Therapeutic Uses, Adverse effects and Contraindications

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  Procainamide  Procainamide is a medication used to treat certain heart rhythm problems, particularly ventricular arrhythmias. It is classified as an antiarrhythmic drug and belongs to the class of medications known as Class Ia antiarrhythmics. Procainamide is available under various brand names, depending on the country and the manufacturer. Some common brand names for procainamide include:  1. Pronestyl 2. Procan SR 3. Procanbid 4. Promine 5. Procan 6. Procain 7. Procan-SR 8. Procanbid Extended Release As with any medication, it's essential to use the specific brand name prescribed by your healthcare provider or pharmacist to ensure you are taking the correct medication and dosage. Mechanism Of Action The MOA (Mechanism of Action) of procainamide involves its effects on cardiac ion channels, particularly sodium channels, which are crucial for the conduction of electrical signals in the heart. Here's a more detailed explanation of the mechanism of action:  1. Sod...

Disopyramide, Structure, Mechanism of action, Drug Interactions, Therapeutic Uses, Adverse effects and Contraindications

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  Disopyramide     Disopyramide is an antiarrhythmic medication used to treat certain types of abnormal heart rhythms (arrhythmias). It belongs to the class of drugs known as Class I antiarrhythmics, which work by blocking certain ion channels in the heart that are involved in generating abnormal electrical signals. The drug is primarily used to treat ventricular arrhythmias, which are irregular heart rhythms that originate in the ventricles, the lower chambers of the heart. By blocking specific ion channels in the heart, disopyramide can help stabilize the heart's electrical activity and restore a normal heart rhythm. Some common brand names for disopyramide include Norpace and Norpace CR (controlled release). It is available in both immediate-release and extended-release formulations. Mechanism Of Action The MOA (Mechanism of Action) of disopyramide involves its effect on the electrical activity of the heart, specifically targeting ion channels in cardiac cells. Disopyr...