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Showing posts with the label Potassium sparing diuretics

Triamterene, Structure, Mechanism of Action, Drug Interactions, Therapeutic Uses, Adverse effects and Contraindications

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Triamterene Triamterene is a medication used to treat fluid retention (edema) and high blood pressure (hypertension). It belongs to a class of drugs known as diuretics or "water pills." Triamterene works by increasing the amount of urine produced by the kidneys, which helps to remove excess fluid and sodium from the body. When used for edema, triamterene is often prescribed in combination with another diuretic called hydrochlorothiazide. This combination medication is commonly known as triamterene/hydrochlorothiazide or simply triamterene HCTZ. Triamterene is primarily available as a generic medication, there are a few common brand names under which it is sold: Dyrenium Maxzide (combination medication with hydrochlorothiazide) Dyazide (combination medication with hydrochlorothiazide) Triamterene/HCTZ (combination medication with hydrochlorothiazide) Maxzide-25 (combination medication with hydrochlorothiazid e) Mechanism Of Action The mechanism of action of triamterene involve...

Eplerenone, Structure, Mechanism of Action, Drug Interactions, Therapeutic Uses, Adverse effects

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Eplerenone Eplerenone, sold under the brand name Inspra, is an aldosterone antagonist type of potassium-sparing diuretic that is used to treat chronic heart failure and high blood pressure, particularly for patients with resistant hypertension due to elevated aldosterone. Some of the commonbrand names under which eplerenone is marketed include: Inspra Eplenerone Cardiostat Apo-Eplerenone (in some countries) Selara (in some countries) Please note that brand names may vary depending on the country and manufacturer. It is always best to consult with a healthcare professional or pharmacist for accurate and up-to-date information about brand names in your specific region. Mechanism Of Action Eplerenone is a medication classified as a mineralocorticoid receptor antagonist. Its mechanism of action involves selectively blocking the binding of aldosterone, a hormone involved in regulating salt and water balance in the body, to its mineralocorticoid receptors. By blocking the mineralocorticoid r...