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Lidocaine, Structure, Mechanism of action, Drug Interactions, Therapeutic Uses, Adverse effects and Contraindications.

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Lidocaine Lidocaine is a commonly used local anesthetic and antiarrhythmic drug. It belongs to the class of medications known as amide local anesthetics. Lidocaine works by blocking nerve signals in a specific area of the body, numbing the region and reducing pain sensations. Lidocaine is available under various brand names, and some of the common ones include: 1.  Xylocaine:  Xylocaine is one of the most well-known brand names for lidocaine and is available in different formulations such as creams, ointments, gels, and injections for local anesthesia. 2.  LidoPatch:  This brand name is often associated with lidocaine patches used for local pain relief, typically applied to the skin to numb the area. 3.  Lidoderm:  Lidoderm is another popular brand name for lidocaine patches used to relieve pain associated with post-herpetic neuralgia, a complication of shingles. 4.  Solarcaine:  Solarcaine is a brand name that offers products containing lidocaine...

Mexiletine, Structure, Mechanism of action, Drug Interactions, Therapeutic Uses, Adverse effects and Contraindications

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                                                Mexiletine Mexiletine is a medication primarily used to treat certain heart rhythm disorders, specifically ventricular arrhythmias. It belongs to a class of drugs known as antiarrhythmics. Mexiletine works by blocking sodium channels in the heart, which helps to stabilize the heart's electrical activity and prevent abnormal heart rhythms. One of the common brand names for Mexiletine is "Mexitil." It is essential to note that brand names may vary depending on the country and the manufacturer. Mechanism Of Action The MOA (Mechanism of Action) of Mexiletine involves its activity as a class Ib antiarrhythmic medication. It primarily affects the electrical properties of cardiac cells, specifically by blocking sodium channels. Sodium Channel Blockade :  Mexiletine inhibits the fast inward sodium current in cardiac cells du...