Digoxin, Structure, Metabolism, Mechanism Of Action, Drug Interactions, Therapeutic Uses, Side Effects and Contraindications
Digoxin Digoxin is a medication commonly used to treat various heart conditions, particularly heart failure and certain irregular heart rhythms (arrhythmias). It is a cardiac glycoside derived from the foxglove plant (Digitalis lanata). The main mechanism of action of digoxin is to increase the strength and efficiency of heart muscle contractions, thereby improving the pumping capacity of the heart. It does this by inhibiting the sodium-potassium ATPase pump, which leads to an increase in intracellular calcium levels in cardiac muscle cells. The higher calcium levels enhance the force of cardiac muscle contractions, resulting in increased cardiac output. Digoxin is available under various brand names, some of which include: 1. Lanoxin 2. Digitek 3. Digox 4. Lanoxicaps 5. Lanoxin-PG (Pediatric drops) It's important to note that the availability of brand names may vary depending on the country and the manufacturer. Always refer to the specific brand name prescribed by your health...