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Showing posts with the label Calcium channel Blockers

Verapamil, Structure, Metabolism, Mechanism Of Action, Drug Interactions, Therapeutic Uses, Side Effects and Contraindications

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Verapamil   Verapamil is a medication commonly used to treat certain heart conditions and high blood pressure (hypertension). It belongs to a class of drugs called calcium channel blockers, which work by relaxing and widening blood vessels, thereby reducing the heart's workload and improving blood flow. Verapamil is available under various brand names, and the availability of these names can vary depending on the country or region. Some common brand names for verapamil include: 1. Calan 2. Isoptin 3. Verelan 4. Covera-HS 5. Tarka (a combination of verapamil and trandolapril) Please note that this is not an exhaustive list, and there may be other brand names for verapamil depending on your location. Always check with your healthcare provider or pharmacist for the specific brand names available in your area. Metabolism Verapamil is primarily metabolized in the liver through a process known as hepatic metabolism. The main pathway of verapamil metabolism involves the cytochrome P450 ...

Diltiazem, Structure, Metabolism, Mechanism Of Action, Drug Interactions, Therapeutic Uses, Side Effects and Contraindications

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  Diltiazem is a medication used primarily for the treatment of high blood pressure (hypertension) and certain heart conditions. It belongs to the class of drugs known as calcium channel blockers. Diltiazem works by inhibiting the movement of calcium ions into the muscle cells of the heart and blood vessels. This action relaxes and widens the blood vessels, which leads to reduced blood pressure and improved blood flow. It also reduces the workload of the heart, making it useful in certain heart conditions. Diltiazem is available under various brand names, and some of the common ones include: 1. Cardizem 2. Cartia 3. Tiazac 4. Dilt-XR 5. Dilacor XR 6. Matzim LA 7. Taztia XT 8. Tildiem 9. Viazem Please note that the availability of these brand names may vary depending on your country and region. Always check with your local pharmacy or healthcare provider to confirm the specific brand names available in your area. Metabolism Diltiazem undergoes extensive metabolism in the liver. The...